Mervyn J Merrilees Selected Research

Versicans (Versican)

1/2017	Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation.
1/2017	Deposition of insoluble elastin by pulmonary fibroblasts from patients with COPD is increased by treatment with versican siRNA.
1/2016	Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma.
8/2015	Knockdown of versican 1 blocks cigarette-induced loss of insoluble elastin in human lung fibroblasts.
8/2014	Versican and the regulation of cell phenotype in disease.
4/2014	Versican and the control of inflammation.
7/2012	Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung.
6/2011	Neointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulation.
5/2008	Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease.
2/2006	Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury.

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Mervyn J Merrilees Research Topics

Disease

4	Chronic Obstructive Pulmonary Disease (COPD) 01/2017 - 05/2008
4	Inflammation (Inflammations) 01/2016 - 05/2004
3	Neoplasms (Cancer) 12/2018 - 04/2014
3	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 12/2018 - 06/2004
3	Neointima 06/2011 - 03/2002
3	Vascular System Injuries 12/2008 - 03/2002
2	Vascular Diseases (Vascular Disease) 08/2014 - 05/2004
1	Tuberous Sclerosis (Bourneville's Disease) 12/2018
1	Acute Lung Injury 01/2017
1	Virus Diseases (Viral Diseases) 01/2017
1	Hypersensitivity (Allergy) 01/2017
1	Pneumonia (Pneumonitis) 01/2017
1	Wounds and Injuries (Trauma) 01/2017
1	Asthma (Bronchial Asthma) 01/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2015
1	Neoplasm Metastasis (Metastasis) 04/2014
1	Rupture 10/2012
1	Cysts 10/2012
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2012
1	Hyperlipidemias (Hyperlipidemia) 06/2011
1	Hypercholesterolemia 06/2011
1	Fibrosis (Cirrhosis) 03/2007
1	Interstitial Lung Diseases (Interstitial Lung Disease) 06/2004
1	Thrombosis (Thrombus) 05/2004
1	Atherosclerosis 05/2004

Drug/Important Bio-Agent (IBA)

12	Versicans (Versican)IBA 01/2017 - 03/2002
5	TropoelastinIBA 01/2017 - 03/2002
5	ElastinIBA 01/2017 - 05/2008
5	Proteoglycans (Proteoglycan)IBA 01/2016 - 05/2004
3	lipoarabinomannan (LAM)IBA 12/2018 - 06/2004
2	LipidsIBA 06/2011 - 05/2004
2	CollagenIBA 06/2011 - 03/2002
1	LigandsIBA 12/2018
1	Poly I-CIBA 01/2017
1	Toll-Like Receptor 3IBA 01/2017
1	Poly CIBA 01/2017
1	Tamoxifen FDA LinkGeneric 01/2017
1	Chondroitin Sulfate ProteoglycansIBA 01/2017
1	Small Interfering RNA (siRNA)IBA 01/2017
1	Hyaluronic Acid (Hyaluronan)IBA 01/2016
1	AntigensIBA 01/2016
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 08/2015
1	SmokeIBA 08/2015
1	Proteins (Proteins, Gene)FDA Link 08/2015
1	Insulin (Novolin)FDA Link 05/2015
1	CytokinesIBA 04/2014
1	GoldIBA 07/2012
1	BiglycanIBA 12/2008
1	GlycosaminoglycansIBA 12/2008
1	elastin-binding proteinsIBA 05/2008
1	Sirolimus (Rapamycin)FDA Link 03/2007
1	Tuberous Sclerosis Complex 2 ProteinIBA 06/2004
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2004
1	Lipoproteins (Lipoprotein)IBA 05/2004
1	EnzymesIBA 05/2004

Therapy/Procedure

1	Immunotherapy 12/2018
1	Artificial Skin 01/2017